Phytolacca species grown in Korea are Phytolacca esculenta, P. americana, and P. insularis. These plants are perennial shrub, roots of which have been used as an indigenous medicine against edema and rheumatism in the Far East Asia including China, Japan, and Korea, since ancient times. Several old dispensatories have described these plants as diuretic agent. The older generation of physicians in U.S.A. also used these plants as a medicine. P. americana was official in the U.S.P. of 1880 and 1890. And it has been listed in the National Formulary and various dispensatories, in which we read that the plant has been recommended as an emetic, a narcotic, and a gargle and as a remedy for chronic rheumatism, granular conjunctivitis, ringworm, parasitic infections of the scalp, other skin diseases, syphilis, and cancer. The young tender shoots, when properly prepared in spring, are edible. especially familiar to many Kentuckians, in fact a nineday poke festival is held annually at Harllan, Kentucky. Europeans have used the purple juice of the berries extensively for coloring their. wines. In Ethiopia the berries of P. dodecandra have been extensively used as a potential molluscacide for the control of bilhaziasis, a disease transmitted by aquatic snails. W. S. Woo reported the anti-inflammatory action of sapogenins as well as saponins from P. esculenta, and described the occurrence and chemistry of Phytolacca triterpenoids. Also, Woo reported constituents of Phytolacca Species. We have been completely determined the structures of three major saponins, B, E, and G of the ten saponins of Phytolacca spp.